eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
Latest News
All of Us Funding Opportunities
January 1, 2023 3:48 PM
NHGRI Research Training & Career Development Annual Meeting
November 11, 2022 7:50 PM
Nature Scientific Reports proposed a special issue entitled Pharmacogenomics for Precision Medicin
October 10, 2022 3:56 PM
NIH Funding Opportunities for Community Organization Partnerships: LOI due Nov. 19. TA Webinar available on Demand
October 10, 2022 3:15 PM
AnVIL Clinical Resource (ACR) Funding Opportunity Announcement
September 9, 2022 5:08 PM
NHGRI published three companion RFAs for the Multi-Omics for Health and Disease Consortium
September 9, 2022 8:21 PM
Recent Publications
Hui D, Xiao B, Dikilitas O, Freimuth RR, Ritchie MD, et al. Quantifying factors that affect polygenic risk score performance across diverse ancestries and age groups for body mass index. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2023;28:437-448.
Hellwege JN, Dorn C, Irvin MR, Limdi NA, Edwards TL, et al. Predictive models for abdominal aortic aneurysms using polygenic scores and PheWAS-derived risk factors. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2023;28:425-436.
Mack T, Sanchez-Roige S, Davis LK. Genetic investigation of the contribution of body composition to anorexia nervosa in an electronic health record setting. Translational psychiatry. 2022 Nov 19;12(1):486.