eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
Recent Publications
Wynn J, Milo Rasouly H, Vasquez-Loarte T, Saami AM, Holm IA, et al. Do research participants share genomic screening results with family members? Journal of genetic counseling. 2021 Oct 19;.
Zanussi JT, Zhao J, Dorn CA, Liu G, Kawai VK. Identifying Potential Therapeutic Applications and Diagnostic Harms of Increased Bilirubin Concentrations: A Clinical and Genetic Approach. Clinical pharmacology and therapeutics. 2021 Oct 8;.
Dickson AL, Daniel LL, Zanussi J, Dale Plummer W, Chung CP, et al. TPMT and NUDT15 Variants Predict Discontinuation of Azathioprine for Myelotoxicity in Patients with Inflammatory Disease: Real-World Clinical Results. Clinical pharmacology and therapeutics. 2021 Sep 28;.