eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
Recent Publications
Taub MA, Conomos MP, Keener R, Iyer KR, Mathias RA, et al. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell genomics. 2022 Jan 12;2(1).
Kullo IJ, Lewis CM, Inouye M, Martin AR, Chatterjee N. Polygenic scores in biomedical research. Nature reviews. Genetics. 2022 Mar 30;.
Wang L, Scherer SE, Bielinski SJ, Muzny DM, Weinshilboum RM, et al. Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study. Genetics in medicine : official journal of the American College of Medical Genetics. 2022 May;24(5):1062-1072.