eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
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Inviting Feedback on the Framework for the NIH Strategic Plan for Disability Health Research FY26-FY30
January 1, 2025 7:38 PM
CTSA Collaborative & Innovative Acceleration (CCIA) Award NOFO and Notice for TA webinar
January 1, 2025 7:37 PM
NHGRI 2025 Training Meeting
December 12, 2024 10:27 PM
Funding Announcement: RFA-HG-25-005
November 11, 2024 2:36 PM
FY25 Bioethics NOSI is Live
October 10, 2024 7:32 PM
NOSI: Administrative supplements to active NIH awards to support replication studies using independent contract resources (NOT-RM-24-013)
October 10, 2024 3:28 PM
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Recent Publications
Wang C, Markus H, Diwadkar AR, Khunsriraksakul C, Jiang B, et al. Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages. Nature communications. 2025 Jan 2;16(1):180.
Roberts DA, Bastarache L, He J, Lewis A, Kertai MD. Updating probability of pathogenicity for RYR1 and CACNA1S exon variants in individuals without malignant hyperthermia after exposure to triggering anesthetics. Pharmacogenetics and genomics. 2025 Feb 1;35(2):65-72.
Reddy IA, Han L, Sanchez-Roige S, Niarchou M, Davis LK. Identification of Transdiagnostic Childhood Externalizing Pathology Within an Electronic Medical Records Database and Application to the Analysis of Rare Copy Number Variation. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2025 Jan 2;:e33020.
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