eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
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Recent Publications
Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Mancuso N, et al. Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity. medRxiv : the preprint server for health sciences. 2024 Nov 20;.
Shelley JP, Shi M, Peterson JF, Van Driest SL, Mosley JD. A polygenic score for height identifies an unmeasured genetic predisposition among pediatric patients with idiopathic short stature. Research square. 2024 Oct 14;.
Obare LM, Bailin SS, Zhang X, Nthenge K, Wanjalla CN, et al. HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression. Research square. 2024 Oct 18;.
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