eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
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NOSI: Supporting the Exploration of Cloud in NIH-supported Research
April 4, 2024 4:31 PM
NOITPs are published
April 4, 2024 4:30 PM
eConsult NOFOs released
January 1, 2024 7:19 PM
Research Training at NIH: Upcoming virtual information sessions (Postbac, Grad, Summer, Postdoc)
November 11, 2023 8:34 PM
Informational Webinar on ELSI PARs – 12/11/23 at Noon
November 11, 2023 3:08 PM
Everything You Ever Wanted to Know About Applying for NIH Grants (But Were Afraid to Ask)
September 9, 2023 3:16 PM
Recent Publications
Middha P, Thummalapalli R, Betti MJ, Yao L, Ziv E, et al. Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis. Nature communications. 2024 Mar 26;15(1):2568.
Lennon NJ, Kottyan LC, Kachulis C, Abul-Husn NS, Kenny EE, et al. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature medicine. 2024 Feb;30(2):480-487.
Li R, Benz L, Duan R, Denny JC, Chen Y, et al. mixWAS: An efficient distributed algorithm for mixed-outcomes genome-wide association studies. medRxiv : the preprint server for health sciences. 2024 Jan 10;.