eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
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Recent Publications
Naderian M, Smith JL, Hamed ME, Dikilitas O, Kullo IJ, et al. Impact of Genetic Risk Factors on Coronary Heart Disease Risk Across the Age Spectrum in Three Major Race/Ethnicity Groups in the United States. medRxiv : the preprint server for health sciences. 2025 Nov 15;.
Brokamp E, Scalici A, Miller-Fleming T, Wu D, Shuey MM. Expanding the Genetic Landscape of Craniofacial Anomalies Through Transcriptome-Wide Association Studies. Research square. 2025 Oct 17;.
Godrich D, Pasteris J, Martin ER, Kunkle B, Alzheimer's Disease Genetics Consortium (ADGC), et al. Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2025 Nov;21(11):e70760.
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