About

about eMERGE (blue) (web)

eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine. In its projects, eMERGE studies and pilots genomic medicine translation  through discovery, implementation, tools, and policy. During Phase I and II, the Network deployed more than 40 electronic phenotype algorithms across more than 55,000 participants with dense genomic data.  Returning clinical results has been implemented or planned for pilot at sites across the Network.  A large-scale survey of patient attitudes regarding data sharing is being sent to 90,000 clinic patients across the country.  A multicenter pilot of returning genome sequence information to electronic medical records (EMRs) for use in healthcare is almost complete.  Themes of genomics, bioinformatics, genomic medicine, ethnics, data sharing, privacy, and community engagement are of particular relevance to eMERGE.

eMERGE was initiated in 2007 and included five biorepositories linked to EMRs.  The network demonstrated that EMR phenotyping to develop cohorts for genome-wide studies was a robust approach to genetic discovery, defined approaches for enhancing privacy of shared EMR data, and engaged patients and communities in consent and data sharing. eMERGE expanded to include 7 clinical sites in 2011 and 2 pediatric sites in 2012.

eMERGE is openly interested in collaborations.  Current external collaborations include the US Air Force, ENCODE, IGNITE, and the larger ELSI (Ethical, Legal, and Social Issues) community.  eMERGE is dedicated to developing tools, identifying best practices, and communicating results for participant consent, data sharing, and returning genomic research results, to benefit the broader medical and scientific communities and the general public.

To learn more about us, visit our eMERGE FAQ page.

In the News

Here's what's happening with eMerge:

08
MAY

The eMERGE Network is excited to share that the MCS NT304, Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in the eMERGE Network; was published...

24
MAR

Two companion RFAs for the PRS Diversity Consortium are now published:

  • Polygenic Risk Score (PRS) Methods and Analysis...

27
FEB

Notice to Encourage Eligible NHGRI Awardees to Apply for PA-18-906 "Research Supplements to Promote Diversity in Health-Related Research”

The Notice of Special Interest (NOSI) on Development of Statistical, Population Genetics, and Computational Methods Related to Polygenic Prediction of Health and Disease in...