eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large scale, high-throughput genetic research in support of implementing genomic medicine.
Many factors contribute to risk of a disease. Some of these factors are internal, like genetics, and others are external, like where someone lives. Over the last several years researchers have discovered that in addition to one gene being associated with a given disease (monogenic factors), many genes across your genome can contribute to the development of a disease (polygenic factors). To learn more about elements that contribute to risk a disease, click here.
Recent Publications
Strom NI, Verhulst B, Bacanu SA, Cheesman R, Hettema JM, et al. Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. medRxiv : the preprint server for health sciences. 2024 Jul 5;.
Vue Z, Murphy A, Le H, Neikirk K, Hinton A Jr, et al. MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes. bioRxiv : the preprint server for biology. 2024 Jul 3;.
Middha P, Thummalapalli R, Quandt Z, Balaratnam K, Ziv E, et al. Germline prediction of immune checkpoint inhibitor discontinuation for immune-related adverse events. medRxiv : the preprint server for health sciences. 2024 Jun 11;.
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