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Notice of Special Interest (NOSI): Administrative supplements to active NIH awards to support replication studies using independent contract resources

The NIH Common Fund has released a Notice of Special Interest (NOSI) to provide support for preparatory activities to enable replication of impactful biomedical studies by an independent contract research organization (CRO). Applications must identify a preclinical study with high potential impact on public health that is amenable to replication by an independent CRO. The study to be replicated may replicate an experiment, replicate the results of a previous computational analysis, or replicate a demonstration of the capabilities of a novel tool, technology, or method. The study must be able to be completed within the one-year budget period. 

• Full Text of the Notice of Special Interest (NOSI):  Administrative supplements to active NIH awards to support replication studies using independent contract resources (NOT-RM-24-013).
• The funding provided by this funding opportunity is not to directly perform replication activities, but to support preparatory activities and engagement with the CRO. The replication studies will be performed by the CRO, and results will not be made public without consent of the original principal investigator(s).
• Applicants must be requesting administrative support to an active NIH-supported parent award to be eligible under this NOSI.
• Applications will be accepted starting through November 15, 2024 by 5:00 PM local time of applicant organization.
• A technical assistance webinar will be held on October 29, 2024 from 4:00-5:00 PM ET. Use this link to register.
• Email Dr. Sahana Kukke and Dr. Michelle Hamlet at CF-Replication@od.nih.govwith any questions. 

Find answers to Frequently Asked Questions (FAQs) on the Replication to Enhance Research Impact Initiative website.