MAGen NOFOs published

May 15, 2024 - 03:13PM - by Sophie Forman

NHGRI, in collaboration with the Office of Data Science Strategy, announces two Notices of Funding Opportunity for the creation of a consortium of MAGen Sites and a Coordinating Center.

UG3/UH3 (Clinical Trial Not Allowed) for MAGen Development Sites:

UG3/UH3(Clinical Trial Not Allowed) for a Coordinating Center

The National Human Genome Research Institute has issued two Notices of Funding Opportunity (NOFO) to solicit applications to explore the feasibility of developing Machine Learning (ML) and Artificial Intelligence (AI) tools that can enhance the accuracy and precision of predicting how individuals with pathogenic genetic variants manifest disease. NHGRI aims to establish a research Consortium, ML/AI Tools to Advance Genomic Translational Research (MAGen), to collaboratively identify both genomic and non-genomic factors influencing disease development in individuals carrying pathogenic genetic variants. The ML/AI tools will leverage existing multimodal genomic and non-genomic data and will be cross validated in genomic translational research settings to ensure the robustness and generalizability of the tools for translational purposes. In addition, the Consortium will explore the ethical, legal, and social implications (ELSI) of integrating ML/AI tools into genomic medicine through the establishment of an ELSI Framework for their development, and through implementation of ELSI research projects. The resources generated by the Consortium will be disseminated to the research community.

NIH Funding Announcement: Research Opportunity Announcement (ROA) “Integrating Clinical Research into Primary Care Settings through Network Research Hubs – A Pilot (OT2)”

May 15, 2024 - 03:12PM - by Sophie Forman

The NIH Common Fund issued a new Research Opportunity Announcement (ROA) “Integrating Clinical Research into Primary Care Settings through Network Research Hubs – A Pilot (OT2).”

The purpose of this limited competition ROA is to invite applications by organizations currently affiliated with and participating in specific existing clinical research networks --to serve as “Network Research Hubs” to conduct clinical research in primary care settings. This opportunity is limited to organizations that focus on serving rural communities and are part of or funded by: NIH Institutional Development Award Clinical and Translational Research (IDeA-CTR) awards, the NIH Clinical and Translational Science Award (CTSA) Program, and/or the Patient-Centered Outcomes Research Institute’s (PCORI) Patient-Centered Clinical Research Network (PCORnet).

Applications should provide plans to leverage existing networks to conduct research in primary care settings with a focus on engaging underrepresented populations, particularly those in rural or underserved areas, and enhancing study inclusivity. Bringing clinical research studies to individuals in their own communities, informed by those communities, and improving clinical research inclusivity will facilitate the generation of a more broadly applicable evidence base that contributes to improved patient outcomes and health equity for all Americans.

Applications are due on June 14, 2024, by 5:00 PM EDT.  

Technical webinars are scheduled for May 14 at 12:00 PM EDT and May 22 at 12:00 PM EDT. Information about the webinars is forthcoming and will be available on the Common Fund website later this week.

The NIH Common Fund encourages collaboration and supports a series of exceptionally high impact, trans-NIH programs. These programs are supported by the Common Fund and managed by the NIH Office of the Director in partnership with the various NIH Institutes, Centers, and Offices. 

The National Institutes of Health (NIH) – “The Nation's Medical Research Agency” – includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical, and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about the NIH and its programs, visit the NIH website.

Webinar: NIH Grants Process: Walk-Through for Beginners

May 01, 2024 - 07:47PM - by Sophie Forman

An NIH guide notice released last week announced a webinar on the “NIH Grants Process: A Brief Walk-Through for Beginners.”

Are you new to working with the NIH grants process? If so, make plans to join your peers as the NIH walks through essential aspects of applying for funding. This event offers participants an opportunity to gain insight into the NIH’s organizational structure and how it funds research, resources to help find the right fit for your research including NIH Notices of Funding Opportunities (NOFOs), an overview of the grants process and peer review, NIH and applicant institution roles/responsibilities, and where to access help along the way.

Hosted by the NIH Office of Extramural Research (OER) and the Center for Scientific Review (CSR), this simulive event includes a short recording, followed by a live Q&A with NIH experts. More than an hour will be devoted to addressing questions submitted during registration and new questions raised during the discussion. There will also be interactive opportunities to test your knowledge of submission policies and grant-related terminology.

  • Webinar: NIH Grants Process: A Brief Walk-Through for Beginners
  • Date: Wednesday, May 15, 2024  
  • Time: 1:00 – 2:30 p.m. ET
  • Registration Required


Anyone new to working with the NIH grants process, whether you are considering applying for funding, or may be assisting with application development. 

How to Participate

  • Visit the NIH Grants Event Page for more information and the registration link.
  • Register for the webinar at any time before or during the event. You will not need to download special software. However, you will need a reliable Internet connection and browser.
  • Submit your questions during the registration process. Some will be used to help develop the presentation, while others will be answered during the Q&A.

Event Resources

The following will be available on this webinar’s NIH Grants Event Page:

  • Presentation slide deck: Posted 24 hours in advance of the webinar.
  • Video recording, transcript, and final presentation slide deck will be available approximately 7–10 business days after the event concludes. 

Reasonable Accommodations 

This webinar will be closed-captioned and include an American Sign Language (ASL) interpreter. Requests for reasonable accommodations should be submitted at least five days before the event to

NOSI: Supporting the Exploration of Cloud in NIH-supported Research

April 10, 2024 - 04:31PM - by Sophie Forman

The Office of Data Science Strategy has released a new Notice of Special Interest (NOSI) that is titled “Supporting the Exploration of Cloud in NIH-supported Research”.  The purpose of this announcement is to explore and test potential opportunities for leveraging cloud solutions to enhance existing NIH activities.  Projects already using cloud may apply to explore and test cloud capabilities not yet leveraged. This initiative is aligned with the NIH Strategic Plan for Data Science, which describes actions aimed at building a better data infrastructure and a modernized data ecosystem.

The link below can be used to access detailed information regarding the NOSI. Please feel free to share the link with any of your colleagues who may have an interest in submitting applications.

Link to the "Supporting the Exploration of Cloud in NIH-supported Research” NOSI:

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