Lessons Learned from eMERGE IIIJanuary 21, 2021 - 03:53PM - by Henry Walker
The Network is very excited to announce the eMERGE III lessons learned paper was just published https://doi.org/10.1016/j.xhgg.2020.100018… Congratulations to the network!
NHGRI announces the next round of the eMERGE NetworkJuly 01, 2020 - 02:19PM - by Jodell Jackson
Read the full press release here. Congratulations to all the sites in the next round of eMERGE!
The new clinical sites will be led by:
- Iftikhar J. Kullo, M.D., at Mayo Clinic, Rochester, Minnesota
- Dan M. Roden, M.D., at Vanderbilt University Medical Center, Nashville, Tennessee
- Elizabeth W. Karlson, M.D., at Brigham and Women’s Hospital, Boston
- Rex Chisholm, Ph.D., at Northwestern University, Chicago
The new enhanced diversity clinical sites will be led by:
- Nita A. Limdi, Ph.D., at University of Alabama, Birmingham
- Eimear E. Kenny, Ph.D., at Icahn School of Medicine at Mount Sinai, New York City
- John B. Harley, M.D., at Cincinnati Children's Hospital Medical Center
- Chunhua Weng, Ph.D., at Columbia University, New York City
- Hakon Hakonarson, M.D., Ph.D., at Children’s Hospital of Philadelphia
- Gail Pairitz Jarvik, M.D., Ph.D., at University of Washington Medical Center, Seattle
The Coordinating Center will be led by:
- Josh F. Peterson, MD, MPH., at Vanderbilt University Medical Center Nashville, Tennessee
Publication Update: MCS NT304 published in the American Journal of Human GeneticsMay 08, 2020 - 01:09PM - by Michelle Stone
The eMERGE Network is excited to share that the MCS NT304, Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in the eMERGE Network; was published on May 7th to American Journal of Human Genetics.
eMERGE Network: RFA PublicationsMarch 24, 2020 - 01:50PM - by Michelle Stone
Two companion RFAs for the PRS Diversity Consortium are now published:
- Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01 Clinical Trial Not Allowed): https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-001.html
- Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01 Clinical Trial Not Allowed): https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-002.html
The goal of the intended FOAs are to establish Study Sites and a Coordinating Center for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Grantees funded under the intended FOAs will form a PRS Diversity Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of PRS to predict health and disease risk across diverse populations, and for a broad range of health and disease measures; and 2) optimizing the integration of large-scale, harmonized genomic and phenotype data to facilitate collaborative analysis, dissemination of PRS-related data, and development of related methods and resources.
Questions may be directed to:
Lucia A. Hindorff, Ph.D, M.P.H.
National Human Genome Research Institute (NHGRI)
Damali N. Martin, Ph.D., M.P.H.
National Cancer Institute (NCI)
Telephone: (240) 276-6746