Publication Update: MCS NT304 published in the American Journal of Human GeneticsMay 08, 2020 - 01:09PM - by Michelle Stone
The eMERGE Network is excited to share that the MCS NT304, Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in the eMERGE Network; was published on May 7th to American Journal of Human Genetics.
eMERGE Network: RFA PublicationsMarch 24, 2020 - 01:50PM - by Michelle Stone
Two companion RFAs for the PRS Diversity Consortium are now published:
- Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01 Clinical Trial Not Allowed): https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-001.html
- Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01 Clinical Trial Not Allowed): https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-002.html
The goal of the intended FOAs are to establish Study Sites and a Coordinating Center for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Grantees funded under the intended FOAs will form a PRS Diversity Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of PRS to predict health and disease risk across diverse populations, and for a broad range of health and disease measures; and 2) optimizing the integration of large-scale, harmonized genomic and phenotype data to facilitate collaborative analysis, dissemination of PRS-related data, and development of related methods and resources.
Questions may be directed to:
Lucia A. Hindorff, Ph.D, M.P.H.
National Human Genome Research Institute (NHGRI)
Damali N. Martin, Ph.D., M.P.H.
National Cancer Institute (NCI)
Telephone: (240) 276-6746
Notice to active NHGRI research grant awardeesFebruary 27, 2020 - 08:03PM - by Michelle Stone
Notice to Encourage Eligible NHGRI Awardees to Apply for PA-18-906 "Research Supplements to Promote Diversity in Health-Related Research”
- PIs of active NHGRI research grants can apply; identify eligible individuals, including those from underrepresented groups, for support and mentorship under the auspices of this supplement opportunity.
- Supplement can support individuals from the undergraduate to the faculty level.
- Activities proposed in the supplement application must fall within the scope and advance the objectives of the parent grant, and also support the research training and professional development of the supplement candidate.
- Applicants are encouraged to provide detailed information and a timeline describing the candidate's expected progression to the next stage in their research career.
- PIs must reference this Notice (NOT-19-010) in the cover letter and application.
- PIs can request travel funds for the diversity supplement awardees to attend the Annual NHGRI Training meeting.
- Supplements should be requested at least 90 days prior to anticipated need and no later than May 15.
- Contacts: Heather Colley (genomic medicine), Tina Gatlin (genome science), and Joy Boyer (ELSI)
Notice of Special InterestJanuary 15, 2020 - 07:22PM - by Michelle Stone
The Notice of Special Interest (NOSI) on Development of Statistical, Population Genetics, and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations has just been published. The purpose of the NOSI is to solicit investigator-initiated applications to develop statistical, computational, and population genetics approaches to modeling polygenic risk in human populations, especially in genetically diverse populations. Questions can be directed to Lucia Hindorff at firstname.lastname@example.org.